Antidiarrheal and Antibacterial Activities of Calpurnia aurea: Benth Seed Different Extracts

Table 3

Effects of the aqueous and 80% methanol seed extracts of C. aurea on normal gastrointestinal transit in mice.

Group	Total length of small intestine (cm)	Distance moved by the charcoal meal (cm)	Percent of transit inhibition	%Inhibition
DW	52.83 ± 1.76	35.50 ± 0.99	32.38 ± 3.31	—
L3	54.00 ± 0.97	25.00 ± 2.88^a1	53.70 ± 5.14^a1c1	29.58%
CAW60	51.67 ± 1.52	31.83 ± 3.74	32.58 ± 7.93^b1	10.34%
CAW120	51.00 ± 2.45	26.67 ± 1.45	47.65 ± 2.01	24.87%
CAW240	53.33 ± 0.95	26.50 ± 1.38	50.17 ± 2.90	25.35%
CAM60	50.83 ± 1.40	31.00 ± 3.48	38.68 ± 7.01	12.68%
CAM120	52.17 ± 0.70	26.83 ± 2.96	48.36 ± 5.94	24.42%
CAM240	53.83 ± 2.51	25.33 ± 2.64	51.70 ± 6.32	28.65%

Values are expressed as Mean ± S.E.M (n = 6), analysis was performed using one way ANOVA followed by Tuckey post-hoc test, Comparison was made among different groups: ^a compared to control, ^b to standard drug, ^c to 60 mg/kg aqueous, , , . DW = distilled water, L = loperamide, CAW = C. aurea water extract and CAM = C. aurea 80% methanol extract.