Antidiarrheal and Antibacterial Activities of Calpurnia aurea: Benth Seed Different Extracts

Table 4

In Vivo antidiarrhea index of aqueous and 80% methanol seed extracts of C. aurea.

Extracts	Dose administered	Delay in defecation (time of onset in minute, dfreq (%))	Gut meal travel distance, (Gmeq (%))	Reduction in intestinal fluid accumulation (%)	Antidiarrheal index (ADI)
Aqueous extract	60 mg/kg	47.37	30.22	33.96	36.50
	120 mg/kg	48.83	57.37	50.94	52.26
	240 mg/kg	55.11	63.39	67.92	61.91
80% methanol extract	60 mg/kg	22.62	49.81	39.62	35.47
	120 mg/kg	36.81	57.37	52.83	48.14
	240 mg/kg	60.80	61.13	62.26	61.39
Loperamide	3 mg/kg	45.69	62.26	49.06	51.87

Values are expressed as % inhibition of different parameters of different models and the combined effect is calculated as ADI.