Inhibition of Aldose Reductase by Novel Phytocompounds: A Heuristic Approach to Treating Diabetic Retinopathy

Table 2

Compounds shortlisted with higher affinity for ALR2 protein, using Glide docking approach.

Compounds	Extra precision (XP) Glide score (kcal/mol)
Epalrestat	−7.641
Eupalitin-3-O-galactoside	−14.425
Andrographolide	−13.490
Picroside II	−13.221
Agnuside	−12.445
Epicatechin-3-gallate	12.434
7-O-Methylwogonin	−11.736
Negundoside	−11.557
Chlorogenic acid	−11.231
Hexahydrocurcumin	−11.140
β-Glucagallin	−11.138
Bisdemethoxycurcumin	−11.117
Luteolin	−10.954
Quercetin dihydrate	−10.841
Galangin	−10.644
Neoandrographolide	−10.501