Inhibition of Aldose Reductase by Novel Phytocompounds: A Heuristic Approach to Treating Diabetic Retinopathy

<table class="table-group" id="tab6"><tr><td><table class="table"><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr class="thead"><td class="align_left">Compound name</td><td class="align_center">IC<sub>50</sub> (nM)</td></tr><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr><td class="align_left">Epalrestat</td><td class="align_center">98.0 nM ± 5.9</td></tr><tr><td class="align_left">Agnuside</td><td class="align_center">22.4 nM ± 8.0</td></tr><tr><td class="align_left">Picroside II</td><td class="align_center">130.0 nM ± 12.0</td></tr><tr><td class="align_left">Eupalitin-3-O-galactoside</td><td class="align_center">27.3 nM ± 5.13</td></tr><tr><td class="align_left">7-O-Methylwogonin</td><td class="align_center">108.0 nM ± 10.56</td></tr><tr class="table-tr"><td colspan="2"><hr class="tbody-hr"/></td></tr></table></td></tr><tr class="table-fn"><td><div>The IC<sub>50</sub> values are expressed as means ± SD for <i>n</i> = 3.<br/></div></td></tr></table>

<div>The IC<sub>50</sub> values of the identified inhibitors of ALR2 human lens.</div>

Evidence-Based Complementary and Alternative Medicine

tab6

Table 6

Table 6: Inhibition of Aldose Reductase by Novel Phytocompounds: A Heuristic Approach to Treating Diabetic Retinopathy 