Integration of Lipidomics and Transcriptomics Reveals the Efficacy and Mechanism of Qige Decoction on NAFLD

Table 2

Differential lipids (DELs) in liver widely-targeted lipidomics by UPLC-MS/MS (n = 6, QGL vs MOD).

Index	Formula	Compounds	m/z	Ion mode	VIP	value	Log2FC
LIPID-P-0016	C19H37NO5	3-Hydroxy-dodecanoyl-carnitine	360.2760	[M + H]+	1.8079	0.0759	−4.1566
LIPID-P-0027	C15H27NO4	Octenoyl-carnitine	286.2025	[M + H]+	1.2305	0.1029	−1.1566
LIPID-P-0715	C48H80NO10P	PS(22 : 2/20 : 5)	862.5598	[M + H]+	1.6372	0.0003	−1.4132
LIPID-P-0840	C51H94O6	TG(14 : 0/16 : 1/18 : 1)	820.7394	[M + NH4]+	1.0090	0.0975	−1.0180
LIPID-P-0898	C51H92O6	TG(14 : 1/16 : 1/18 : 1)	818.7237	[M + NH4]+	1.1005	0.1046	−1.3527
LIPID-P-0900	C51H92O6	TG(14 : 0/16 : 1/18 : 2)	818.7237	[M + NH4]+	1.3069	0.0637	−1.0904
LIPID-P-0974	C51H90O6	TG(14 : 1/14 : 1/20 : 2)	816.7081	[M + NH4]+	1.2559	0.0663	−1.2510
LIPID-P-0976	C51H90O6	TG(14 : 0/16 : 1/18 : 3)	816.7081	[M + NH4]+	1.3677	0.0625	−1.2017
LIPID-P-1032	C53H92O6	TG(16 : 0/16 : 1/18 : 4)	842.7237	[M + NH4]+	1.2610	0.0762	−1.2353
LIPID-P-1036	C53H92O6	TG(14 : 0/18 : 2/18 : 3)	842.7237	[M + NH4]+	1.5812	0.0190	−1.0030
LIPID-P-1081	C53H90O6	TG(14 : 0/18 : 3/18 : 3)	840.7081	[M + NH4]+	1.5392	0.0118	−1.0117
LIPID-P-1122	C55H92O6	TG(14 : 0/18 : 4/20 : 3)	866.7237	[M + NH4]+	1.6973	0.0061	−1.0558
LIPID-P-1123	C55H92O6	TG(16 : 1/16 : 1/20 : 5)	866.7237	[M + NH4]+	1.6026	0.0093	−1.2570
LIPID-P-1155	C57H94O6	TG(14 : 0/20 : 3/20 : 5)	892.7394	[M + NH4]+	1.5143	0.0247	−1.0425
LIPID-P-1176	C57H92O6	TG(18 : 1/18 : 4/18 : 4)	890.7237	[M + NH4]+	1.6034	0.0224	−1.3360
LIPID-P-1190	C57H90O6	TG(18 : 2/18 : 4/18 : 4)	888.7081	[M + NH4]+	1.5834	0.0152	−1.0594