Wound Healing and Antioxidant Properties of 80% Methanol Leaf Extract of Verbascum sinaiticum (Scrophulariaceae): An Ethiopian Medicinal Plant

Table 3

Changes in excised wound size after topical application of the 5% and 10% extract ointment of Verbascum sinaiticum on rats.

Wound area (mm^2) postwounding days
Groups	2	4	6	8	10	12	14	16
BO	295.0 ± 2.54	283.8 ± 2.81	260.0 ± 2.3	247.9 ± 29.8	188.6 ± 2.00	153.9 ± 3.55	122.1 ± 2.49	94.3 ± 3.52
NFO (0.02%)	271.3 ± 12.8^a3	198.5 ± 5.3^a2	167.6 ± 11^a3	130.1 ± 17.7^a3	104.2 ± 16.5^a3	78.9 ± 18.5^a3	57.8 ± 22.39^a2	33.5 ± 22.8^a3
5% extract ointment	258.3 ± 3.5^a3	220.0 ± 13.4^a3	188.5 ± 13.3^a2	144 ± 39.9^a3	104.5 ± 11.05^a3	81.89 ± 14.8^a3	51.3 ± 18.25^a3	23.9 ± 13.7^a3
10% extract ointment	261.2 ± 6^a3	203.2 ± 3.6^a3	162.7 ± 5.57	131.2 ± 12.5^a3	118.1 ± 3.3^a3	99.2 ± 8.52^a3	62.1 ± 14.06^a2	24.9 ± 10.6^a3

Values are expressed as mean ± S.E.M (n = 6); all superscripts indicate significance. a compared to control group; 2 = , 3 = ; numbers from 2 to 16 indicate the day on which contraction rate measurement was taken; BO = base ointment; NFO = nitrofurazone ointment.