Utilizing Network Pharmacology and Molecular Docking Integrated Surface Plasmon Resonance Technology to Investigate the Potential Targets and Mechanisms of <i>Tripterygium wilfordii</i> against Pulmonary Artery Hypertension

<table class="table-group" id="tab4"><tr><td><table class="table"><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr class="thead"><td class="align_left">Target</td><td class="align_center">Degree</td><td class="align_center">Betweenness centrality</td><td class="align_center">Closeness centrality</td></tr><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr><td class="align_left">CASP3</td><td class="align_center">8</td><td class="align_center">0.09695571</td><td class="align_center">0.50159744</td></tr><tr><td class="align_left">PARP1</td><td class="align_center">5</td><td class="align_center">0.04744058</td><td class="align_center">0.48307692</td></tr><tr><td class="align_left">BCL2</td><td class="align_center">5</td><td class="align_center">0.04744058</td><td class="align_center">0.48307692</td></tr><tr><td class="align_left">BAX</td><td class="align_center">4</td><td class="align_center">0.01657181</td><td class="align_center">0.39546599</td></tr><tr><td class="align_left">TNF</td><td class="align_center">4</td><td class="align_center">0.03692728</td><td class="align_center">0.45772595</td></tr><tr class="table-tr"><td colspan="4"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>Core target of <i>Tripterygium wilfordii</i>.</div>

Evidence-Based Complementary and Alternative Medicine

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Table 4

Table 4: Utilizing Network Pharmacology and Molecular Docking Integrated Surface Plasmon Resonance Technology to Investigate the Potential Targets and Mechanisms of <i>Tripterygium wilfordii</i> against Pulmonary Artery Hypertension 

Table 4 | Utilizing Network Pharmacology and Molecular Docking Integrated Surface Plasmon Resonance Technology to Investigate the Potential Targets and Mechanisms of Tripterygium wilfordii against Pulmonary Artery Hypertension 