Preclinical Pharmacokinetics, Biodistribution, and Acute Toxicity Evaluation of Caerin 1.9 Peptide in Sprague Dawley Rats

Figure 3

Mean and standard deviation of body weight over time in acute toxicology experiment of male and female SD rats with single or repeated injection. (a) and (b) are the body weight changes of male and female rats with single subcutaneous injection of different concentrations of F3. (c) shows the body weight changes of rats after 14 consecutive days of subcutaneous injection of F3. The body weight of rats after an overnight fast was measured on the 15th day. The body weights of male and female rats show a proportionate increase during the repeated acute toxicology experiment.

(a)

(b)

(c)