Effects of Hibiscus sabdariffa Calyxes Aqueous Extract on Antioxidant Status and Histopathology in Mammary Tumor-Induced in Rats

Table 3

Effects of H. sabdariffa calyxes extract on some markers of oxidative stress after 21 weeks post-DMBA exposition.

	NOR	DMBA	TAMOX + DMBA	H. sabdariffa + DMBA
				125	250	500
Oxidative stress markers
(i) MDA (mM/mg of proteins)	4.69 ± 1.81	4.65 ± 0.19	5.96 ± 0.55	2.47 ± 0.50^∗	3.92 ± 0.63	3.65 ± 0.93
(ii) SOD (unit/mg of proteins)	97.60 ± 0.11	97.33 ± 0.30	99.53 ± 0.17^∗∗	99.33 ± 0.20^∗∗	99.45 ± 0.10^∗∗	99.33 ± 0.20^∗∗
(iii) Catalase (mM de H2O2/min/mg of proteins)	0.27 ± 0.0	0.41 ± 0.02^###	0.27 ± 0.01^∗∗∗	0.28 ± 0.01^∗∗∗	0.36 ± 0.01^∗∗	0.36 ± 0.01^∗
(iv) Nitric oxide (NO)	51.42 ± 0.56	51.59 ± 0.60	56.84 ± 0.24^∗∗∗	44.67 ± 5.27	57.51 ± 0.22	56.80 ± 0.17