Research Article
Traditional Chinese Medicine Syndromes are Associated with Driver Gene Mutations and Clinical Characteristics in Patients with Lung Adenocarcinoma
Table 7
Associations between traditional Chinese medicine syndromes and cancer metastasis.
| Metastasis | TCM syndrome (n) | Lung-spleen Qi deficiency | Yin deficiency and internal heat | Qi and Yin deficiency | Qi stagnation and blood stasis | Yin and Yang deficiency | |
| Lung | Yes | 13 | 11 | 15 | 6 | 4 | 0.925 | No | 19 | 18 | 24 | 13 | 4 | Brain | Yes | 10 | 5 | 7 | 5 | 4 | 0.251 | No | 22 | 24 | 32 | 14 | 4 | Bone | Yes | 13 | 15 | 13 | 11 | 7 | 0.043 | No | 19 | 14 | 26 | 8 | 1 | Liver | Yes | 4 | 4 | 2 | 3 | 0 | 0.558 | No | 28 | 25 | 37 | 16 | 8 | Pleura | Yes | 12 | 4 | 8 | 6 | 3 | 0.206 | No | 20 | 25 | 31 | 13 | 5 | Lymph node | Yes | 20 | 22 | 26 | 14 | 4 | 0.236 | No | 12 | 7 | 13 | 5 | 4 | Multiorgan | Yes | 18 | 16 | 18 | 12 | 5 | 0.751 | No | 14 | 13 | 21 | 7 | 3 |
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Multiorgan metastasis refers to metastasis identified in ≥2 organs. Compared with Qi stagnation and blood stasis, . |