Research Article
Exploration of the Components and Pharmacological Mechanisms of Keyin Pill-Induced Liver Injury Based on Network Pharmacology
Table 2
Core targets of PPI and compound-target-pathway network.
| Target | PPI degree | Compound-target-pathway degree |
| IL6 | 63 | 11 | MAPK3 | 59 | 9 | CASP3 | 58 | 15 | TNF | 57 | 13 | MAPK8 | 57 | 10 | CYCS | 50 | 7 | MAPK1 | 49 | 9 | IL1B | 49 | 9 | CXCL8 | 46 | 10 | CCL2 | 43 | 6 | CASP8 | 40 | 12 | MAPK14 | 40 | 9 | RELA | 39 | 15 | FOS | 38 | 10 | CASP9 | 37 | 8 | NFKBIA | 33 | 7 | NFKB1 | 32 | 13 | NOS2 | 32 | 18 | FASLG | 32 | 6 | CYP2E1 | 31 | 6 | CYP3A4 | 31 | 6 |
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