Spectrum-Efficacy Relationships between GC-MS Fingerprints of Essential Oil from Valerianae Jatamansi Rhizoma et Radix and the Efficacy of Inhibiting Microglial Activation
Table 3
The secretion and mRNA expression of IL-6 and IL-1β in microglial cells.
Group
ELISA
mRNA
IL-6
IL-1β
IL-6
IL-1β
Control
1.000
1.000
1.000
1.000
Model
1.421 ± 0.107##
1.788 ± 0.135##
3.054 ± 0.235###
3.609 ± 0.325###
S1
1.081 ± 0.067∗
1.230 ± 0.132∗
2.133 ± 0.181∗
2.590 ± 0.110∗
S2
1.016 ± 0.067∗
1.296 ± 0.155∗
2.667 ± 0.208
3.006 ± 0.250
S3
0.949 ± 0.039∗∗
1.178 ± 0.159∗
2.442 ± 0.161∗
2.459 ± 0.088∗∗
S4
1.052 ± 0.088∗
1.231 ± 0.075∗∗
1.793 ± 0.246∗∗
2.487 ± 0.201∗
S5
1.177 ± 0.083
1.233 ± 0.117∗
2.632 ± 0.169
2.324 ± 0.179∗∗
S6
1.050 ± 0.021∗∗
1.053 ± 0.083∗∗
2.307 ± 0.254∗
1.954 ± 0.281∗∗
S7
1.015 ± 0.058∗∗
0.978 ± 0.030∗∗
2.462 ± 0.134∗
2.188 ± 0.292∗
S8
1.204 ± 0.125
1.196 ± 0.149∗
2.539 ± 0.242
2.501 ± 0.139∗
S9
1.233 ± 0.127
1.162 ± 0.095∗∗
2.673 ± 0.241
2.340 ± 0.066∗∗
S10
1.014 ± 0.090∗
1.360 ± 0.063∗
1.868 ± 0.136∗∗
2.369 ± 0.133∗∗
S11
0.984 ± 0.023∗∗
1.192 ± 0.103∗∗
2.160 ± 0.156∗
2.247 ± 0.090∗∗
S12
0.968 ± 0.033∗∗
1.170 ± 0.016∗∗
2.036 ± 0.098∗∗
2.556 ± 0.320∗
S13
1.007 ± 0.117∗
1.184 ± 0.169∗
1.909 ± 0.172∗∗
2.281 ± 0.244∗∗
S14
0.913 ± 0.032∗∗
1.346 ± 0.112∗
2.067 ± 0.142∗∗
2.256 ± 0.317∗
## < 0.01, ### < 0.001 were significant difference between the model group and control group; ∗ < 0.05, ∗∗ < 0.01 were considered statistically significant between the treatment groups and model group ( ± s, n = 3).
