Study on the Mechanism of Qing-Fei-Shen-Shi Decoction on Asthma Based on Integrated 16S rRNA Sequencing and Untargeted Metabolomics

Figure 3

QFSS treatment improved the pathological changes in mice with asthma. (a, c) HE staining showed that QFSS treatment improved the pathological changes (disorderly bronchial epithelial cell arrangement, bronchial smooth muscle thickening, and a large number of inflammatory cells) in lung (a) and decreased the inflammation score (c). Black arrows indicated the impaired structure of bronchus and red arrows indicated the infiltration of proinflammatory cells (magnification: 200×). (b, d) Masson staining showed that QFSS reduced the deposition of collagen contents in lung (b) and decreased the Masson staining score (d) in asthmatic model mice (magnification: 200×).

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