Vascular Endothelial Growth Factor Single Nucleotide Polymorphism +405 G/C (rs2010963) is associated with Levels, Infection Severity, and Amputation among South Indian Diabetic Foot Ulcer Patients

Table 5

Genetic association of VEGF +405G/C (rs2010963) genotypes with ulcer grades and the outcome of treatment procedures for DFU.

SNP (n = 745)	Grades of ulcer		Outcome of treatment procedure
	Grade I and II OR (95% CI)	Grade III and IV OR (95% CI)	Minor amputation OR (95% CI)	Minor amputation OR (95% CI)
GG vs GC + CC	Ref		Ref
CC vs GG + GC	2.58 (1.9–42.7); 0.08	4.31 (1.5–78.8); 0.0001	1.24 (1.19–3.51); 0.83	1.97 (1.07–2.74); 0.004