Effects of Intensive Glycemic Control on Serum Exosome miR-126-3p and miR-125b-1-3p Levels and Wound Healing in Patients with Diabetic Ulcers

Figure 3

Correlation analysis of serum exosome microRNAs with wound healing rate and blood glucose. The levels of serum exosome miR-126-3p and miR-125b-1-3p before and after glycaemic control are positively correlated with wound healing rate, (a–d). Serum exosome miR-126-3p levels after treatment are negatively correlated with fasting blood glucose (FBG) levels after treatment, (e). Serum exosome miR-126-3p level after treatment has no significant correlation with 2-hour postprandial blood glucose (2 h PBG) levels after treatment, (f). Serum exosome miR-125b-1-3p levels after treatment have no significant correlation with after treatment FBG (g) and 2 h PBG (h), all . Fasting blood glucose before (i) and after (j) treatment is negatively correlated with wound healing rate, all . There is no obvious correlation between 2 h PBG and wound healing rate before treatment, (k). 2 h PBG is negatively correlated with wound healing rate after treatment, (l).

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