Effects of Intensive Glycemic Control on Serum Exosome miR-126-3p and miR-125b-1-3p Levels and Wound Healing in Patients with Diabetic Ulcers

Figure 4

The relative expression levels of serum exosome miR-126-3p and miR-125b-1-3p before and after treatment in the two groups, and the differences in expression levels between groups. The level of serum exosome miR-126-3p in the intensive glycemic control group (a) and the conventional glycemic control group (b) increased after treatment, . After treatment, the serum exosome miR-126-3p level in the intensive glycemic control group was higher than that of the conventional glycemic control group, (c). The level of serum exosome miR-125b-1-3p increased in the intensive glycemic control group (d) and the conventional glycemic control group (e) after treatment, and the differences are statistically significant, all . There was no significant difference in serum exosome miR-125b-1-3p level in the intensive glycemic control group after further comparison, (f). , .

(a)

(b)

(c)

(d)

(e)

(f)