Effects of Intensive Glycemic Control on Serum Exosome miR-126-3p and miR-125b-1-3p Levels and Wound Healing in Patients with Diabetic Ulcers
Table 3
Comparison of clinical data within and between groups () or ().
Characteristics
Intensive glycemic control group ( = 21)
Conventional glycemic control ( = 24)
Before treatment
After treatment
Difference before and after treatment
Before treatment
After treatment
Difference before and after treatment
FBG (mmol/L)
10.43 ± 3.82
5.49 ± 0.64
3.90 (2.15, 7.70)
10.64 ± 2.86
7.97 ± 1.76###
1.95 (1.00, 2.70)▲###
2 h PBG (mmol/L)
13.91 ± 3.18
7.53 ± 1.74
4.80 (3.90, 9.15)
13.51 ± 2.76
10.72 ± 1.86###
2.55 (−0.70, 5.13)▲###
SYS (mmHg)
132.24 ± 29.70
124.33 ± 21.27
3.00 (−5.00, 26.00)
138.25 ± 21.68
128.88 ± 17.43
5.00 (1.00, 11.50)▲
DIA (mmHg)
81.90 ± 16.69
76.62 ± 13.00
−6.00 (−14.00, 10.00)
80.67 ± 12.41
78.63 ± 11.00
−1.00 (−3.00, 3.75)▲
Albumin (g/L)
30.54 ± 6.68
32.53 ± 6.51
0.60 (−2.30, 4.50)
33.82 ± 6.71
35.25 ± 5.82
0.50 (0.00, 6.15)▲
Blood (μmol/L)
101.55 ± 46.05
99.82 ± 42.73
−1.00 (−12.00, 10.25)
86.76 ± 26.78
82.65 ± 25.94
−0.50 (−11.00, 9.75)▲
Blood uric acid (μmol/L)
277.00 ± 79.47
285.45 ± 104.645
16.00 (−15.00, 23.00)
303.31 ± 100.47
290.44 ± 106.11
−17.00 (−89.25, 74.50)▲
Hb (g/L)
113.06 ± 21.42
103.89 ± 24.30
−6.50 (−16.50, 0.50)
120.95 ± 22.40
111.68 ± 26.07
−14.50 (−22.75, 3.50)▲
WBC (×109/L)
11.13 ± 4.37
7.34 ± 3.22
−3.59 (−8.51, 0.31)
8.88 ± 2.01
8.09 ± 3.61
−0.70 (−2.37, 0.83)▲#
Percentage of neutrophils (%)
72.81 ± 18.1
63.21 ± 13.01
−11.25 (−20.35, −5.08)
71.44 ± 12.69
65.45 ± 11.66
−4.95 (−13.20, 0.20)▲
Wound (cm2)
5.60 (1.87, 20.73)
2.22 (0.54, 5.85)△
61.55 ± 21.54
8.85 (1.99, 21.31)
6.49 (1.13, 14.09)△▲###
35.70 ± 15.74###
In the column of wound area, the difference before and after treatment is the wound healing rate. Wound healing rate = (original wound area − unhealed wound area)/original wound area × 100%. △Wilcoxon rank-sum test, ▲Mann–Whitney U test. Intragroup comparison, ,, and . Comparison between groups (including the difference before and after treatment), #, and ###.
