Research Article

[Retracted] POU Class 2 Associating Factor 1 Exerts a Protective Effect on the Respiratory Syncytial Virus-Induced Acute Bronchiolitis by the NF-κB Pathway

Figure 3

POU2AF1 attenuated lung injury and inflammation in RSV-infected mice. (a) RT-qPCR measured POU2AF1 level in RSV mice after injection of adv-POU2AF1 (n = 6) and adv-NC (n = 6). (b) HE staining detected histopathological features in the lung tissue of RSV mice under POU2AF1 overexpression. (c, d) Cell counts for neutrophils and monocytes in the lung tissue of RSV mice under POU2AF1 overexpression. (e–h) ELISA assessed INF-γ, TNF-α, IL-1β, and IL-6 concentrations in the lung tissue of RSV mice under POU2AF1 overexpression. , , RSV + Adv-POU2FA1 vs. RSV + Adv-NC group.
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