Naringin Prevents Cognitive Dysfunction in Aging Rats by Inhibiting Toll-Like Receptor 4 (TLR4)/NF-κB Pathway and Endoplasmic Reticulum Stress

Figure 3

Naringin attenuates D-galactose-induced inflammatory response and oxidative stress in the rat hippocampus. (a)–(c): the levels of proinflammatory cytokines IL-1β (a), IL-6 (b), and MCP-1 (c) in the hippocampus of rats in each group detected by ELISA assay; (d)/(e): the levels of oxidative stress substance MDA (d) and the activity of GSH-Px (e) in the hippocampus of rats in each group detected by the biochemical kit;  < 0.01, vs. control;  < 0.05 and  < 0.01, vs. D-gal.

(a)

(b)

(c)

(d)

(e)