Triterpene and Steroids from Ludwigia abyssinica A. Rich (Onagraceae) Displayed Antimicrobial Activities and Synergistic Effects with Conventional Antibiotics
Table 1
Antimicrobial activity (MIC and MMC in µg/mL) of Ludwigia abyssinica components and reference antibiotics.
Extracts/compounds
Inhibition parameters
E. coli
S. flexneri
S. aureus
C. tropicalis
C. albicans
C. neoformans
MeOH extract
MIC
128
128
64
256
512
128
MMC
128
128
64
256
1024
256
MMC/MIC
1
1
1
1
2
2
EtOAc extract
MIC
64
64
64
128
128
128
MMC
128
64
64
256
256
128
MMC/MIC
2
1
1
2
2
1
1
MIC
32
32
16
64
64
32
MMC
64
64
32
>256
>256
64
MMC/MIC
2
2
2
—
—
2
2
MIC
32
64
128
64
64
32
MMC
64
128
>256
>256
>256
>256
MMC/MIC
2
2
—
—
—
—
3
MIC
64
64
32
64
128
64
MMC
128
128
64
>256
>256
>256
MMC/MIC
2
2
2
—
—
—
Ref
MIC
16
16
1
0.5
1
2
MMC
16
16
1
0.5
1
2
MMC/MIC
1
1
1
1
1
1
—: not determined; MIC: minimum inhibitory concentration; MMC minimum microbicidal concentration; : fluconazole and amoxycillin for yeasts and bacteria, respectively.
