Preclinical Trial of Ocotea puberula (Rich.) Nees (“Canela-Guaicá”) in Wound Healing: Validation of a Traditional Medicine Practice Used by Indigenous Groups in Southern Brazil

Table 1

Wound healing index (WHI) for the experimental groups at different time intervals.

Animal group	WHI (%)
	After 7 days of injury	After 14 days of injury	After 21 days of injury
	Mean ± SD	Mean ± SD	Mean ± SD
CGBE	−7.8 ± 1.7^a	+64.1 ± 3.2^a	+95.4 ± 3.3^a
Negative control	+1.8 ± 1.1^b	+63.6 ± 4.7^a	+87.8 ± 5.9^a,b
Positive control	−5.5 ± 2.2^a	+68.9 ± 4.5^a	+78.8 ± 4.9^b

one-way nonparametric ANOVA (Kruskal–Wallis test); different letters on the columns indicate the statistical difference . Note. CGBE, “canela-guaicá” bark extract; SD, standard deviation.