Garlic Extract Participates in the Proliferation and Apoptosis of Nonsmall Cell Lung Cancer Cells Via Endoplasmic Reticulum Stress Pathway

<div>Z-Ajoene-induced NSCLC cell apoptosis is associated with enhanced ERS. (a) Flow cytometry revealed reduced apoptosis in cells co-treated with Z-ajoene and 4-PBA (an ERS inhibitor). (b) Western blot showed lower Bax, cleaved caspase 3, and cleaved caspase 9 expressions and higher Bcl-2 expression detected in cells cotreated with Z-ajoene and 4-PBA versus Z-ajoene-treated controls.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 4

Figure 4: Garlic Extract Participates in the Proliferation and Apoptosis of Nonsmall Cell Lung Cancer Cells Via Endoplasmic Reticulum Stress Pathway 