Development of an Effective Acne Treatment Based on CBD and Herbal Extracts: Preliminary In Vitro, Ex Vivo, and Clinical Evaluation

Figure 2

The topical formulation containing the natural mixture (“formula”) attenuates LPS-induced inflammation. Inflammation was inflicted in the ex vivo human skin model by 5 µg/ml LPS and treated with the formulated natural mixture for 48 hr. (a) Epidermal viability was evaluated by MTT. (b, c) The quantification of IL-8 and IL-6 by ELISA, respectively. n = 3; /# depicts significance in comparison to the control or LPS-stimulated group, respectively.

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(b)

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