Network Pharmacology and Molecular Docking Explore the Mechanism of Mubiezi-Yinyanghuo Herb Pair in the Treatment of Rheumatoid Arthritis

Figure 7

Molecular docking visualization. (a) GSK3B-Yinyanghuo C (−9.4 kcal/mol), (b) ICAM1-bessisterol (−8.0 kcal/mol), (c) CASP8-oleanolic acid (−8.9 kcal/mol), (d) CASP3-3R,4aR,6aS,6bS,8aS,11R,12aR,14bS)-4,4,6a,6b,8a,11,14b-heptamethyl-11-methylol-1,2,3,4a,7,8,9,10,12,12a,13,14-dodecahydropicen-3-ol (−8.8 kcal/mol), (e) JUN-Yinyanghuo A (−7.3 kcal/mol), (f) HMOX1-8-(3-methylbut-2-enyl)-2-phenyl-chromone (−9.3 kcal/mol), (g) PPARG-8-(3-methylbut-2-enyl)-2-phenyl-chromone (−9.7 kcal/mol), (h) PTGS2-Yinyanghuo C (−10.7 kcal/mol), and (i) HK2-Yinyanghuo C (−9.6 kcal/mol).

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