Evidence-Based Complementary and Alternative Medicine

Research Article

Phytochemical Screening, Toxic Effects, and Antimicrobial Activity Studies of Digitaria abyssinica (Hochst. ex A.Rich.) Stapf (Poaceae) Rhizome Extracts against Selected Uropathogenic Microorganisms

Table 2

Showing effects of D. abyssinica extracts on female Wistar rats wellness parameters and LD50 at 2000 mg/kg oral single-dose.
Wellness parameterObservation after
30 minutes4 hours24 hours48 hours7 days14 days
EGRCGREGRCGREGRCGREGRCGREGRCGREGRCGR
Skin and fur appearanceNormalNormalNormalNormalNormalNormalNormalNormalNormalNormalNormalNormal
Fecal matter consistencyNormalNormalNormalNormalNormalNormalNormalNormalNormalNormalNormalNormal
Urination and urine appearanceNormalNormalNormalNormalNormalNormalNormalNormalNormalNormalNormalNormal
Mucous membrane appearanceNormalNormalNormalNormalNormalNormalNormalNormalNormalNormalNormalNormal
ItchingAbsentAbsentAbsentAbsentAbsentAbsentAbsentAbsentAbsentAbsentAbsentAbsent
SalivationNormalNormalNormalNormalNormalNormalNormalNormalNormalNormalNormalNormal
Convulsions and tremorsAbsentAbsentAbsentAbsentAbsentAbsentAbsentAbsentAbsentAbsentAbsentAbsent
BreathingNormalNormalNormalNormalNormalNormalNormalNormalNormalNormalNormalNormal
ComaAbsentAbsentAbsentAbsentAbsentAbsentAbsentAbsentAbsentAbsentAbsentAbsent
Somatomotor activityNormalNormalNormalNormalNormalNormalNormalNormalNormalNormalNormalNormal
AggressionAbsentAbsentAbsentAbsentAbsentAbsentAbsentAbsentAbsentAbsentAbsentAbsent
GroomingNormalNormalNormalNormalNormalNormalNormalNormalNormalNormalNormalNormal
EyesNormalNormalNormalNormalNormalNormalNormalNormalNormalNormalNormalNormal
Mortality/deathNoneNoneNoneNoneNoneNoneNoneNoneNoneNoneNoneNone
Key: EGR—experimental group of female Wistar rats (administered with the studied plant extracts); CGR—control group of female Wistar rats (administered with physiological saline only).