Chromolaena odorata (L.) R. M. King and H. Robinson Leaves Aqueous Extract Improves the Femoral Head in Ethanol-Induced Osteonecrosis in Rats

Figure 7

Microphotographs of the femoral head (HE 25x and HE 100x) in ethanol-induced osteonecrosis. C. odorata 150, C. odorata 300, and C. odorata 600: rats treated concomitantly with the plant extract and alcohol at doses of 150, 300, and 600 mg/kg; Diclo1: rats treated concomitantly with alcohol and diclofenac at a dose of 1 mg/kg. BR: bone resorption, PO: perichondrium, C: chondrocyte, EC: empty chondroplast, CP: chondroplast, ON: osteonecrosis TD: tidemark, normal control: rats receiving distilled water, alcohol control 1: rats receiving ethanol 40° (3 g/kg) for 12 weeks.