Research Article
Novel Benzothiazole Derivatives Synthesis and its Analysis as Diuretic Agents
Table 1
Lipinski filtering rule of five.
| Compound | Molecular weight | Hydrogen bond donors | Hydrogen bond acceptors | Log p | Molar refractivity |
| IIIa | 322 | 0 | 7 | 1.22 | 75.45 | IIIb | 322 | 0 | 7 | 1.15 | 76.10 | IIIc | 322 | 0 | 7 | 1.73 | 76.82 | IIId | 352 | 0 | 5 | 2.10 | 78.31 | IIIe | 352 | 0 | 5 | 1.78 | 78.10 | IIIf | 352 | 0 | 5 | 1.78 | 78.10 | IIIg | 341.50 | 0 | 6 | 2.14 | 74.35 | IIIh | 341.50 | 0 | 6 | 2.14 | 74.35 | IIIi | 341.50 | 0 | 6 | 2.14 | 74.35 | Standard | 216.00 | 0 | 7 | 0.30 | 40.97 |
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