Novel Benzothiazole Derivatives Synthesis and its Analysis as Diuretic Agents

Table 7

Electrolyte excretion of IIIb and IIIe derivatives.

Treatment	Dose	Electrolyte Excretion Index
		Na^+	K^+
Control	0.9% NaCl	125.83 ± 1.16	43.33 ± 1.86
Urea	1 gm/kg	144.83 ± 1.94	54.55 ± 3.14
Acetazolamide	25 mg/kg	193.83 ± 3.18	76.33 ± 3.66
	45 mg/kg	283.00 ± 2.75	136.83 ± 3.24
IIIb	25 mg/kg	215.33 ± 3.14	84.5 ± 3.01
	45 mg/kg	282.83 ± 2.41	144.33 ± 1.63
IIIe	25 mg/kg	188.83 ± 3.70	69.33 ± 2.16
	45 mg/kg	277.5 ± 2.48	123.66 ± 1.75

Results are presented as mean standard error of the mean (n = 6), with , , (Dunnett’s multiple comparison test) and one way ANOVA. Na⁺ = sodium index, K⁺ = potassium index.