Antimalarial Properties of Sida cordifolia L. Leaf Extract in Mice: Survivability Depends Less on Parasitaemia Suppression

Table 1

Effect of S. cordifolia extract on P. berghei-infected mice.

	Suppressive test		Curative test
Dose mg/kg	% of parasitaemia suppression	Median survival time	% of parasitaemia suppression	Median survival time
NC	0.00	9	0.00	8
50	42.96 ± 0.32^a	13	37.34 ± 0.25^a	9.5
100	53.49 ± 0.25^a	16.5	47.52 ± 0.42^a	13.5
200	66.13 ± 0.27^a	19.5	53.80 ± 1.12^a	17
400	76.90 ± 0.64^a	26	61.50 ± 0.97^a	25.5
PC	95.12 ± 0.18^a	29.5	92.44 ± 0.16^a	29.5

Values were presented as mean ± SEM; n = 4; NC: vehicle-treated group; PC: positive control group (artesunate treated). ^aValues were significantly different at when compared with the negative control (NC).