Research Article

Cedrus deodara: In Vivo Investigation of Burn Wound Healing Properties

Table 5

Histological features of burn wound healing with different experimental groups.

GroupsEpitheliogenesis score (n = 5)Number of inflammatory cells (×103)aNeovascularization (blood vessels/5HPF)a,bCollagen density (%)a,b

PC0 (7 d)128.0 ± 5.6 (7 d)5.2 ± 0.8 (7 d)29.4 ± 3.8 (7 d)
1 (14 d)74.0 ± 9.4 (14 d)35.2 ± 7.3 (14 d)39.8 ± 3.7 (14 d)
4 (21 d)27.4 ± 4.2 (21 d)9.0 ± 2.0 (21 d)50.6 ± 8.79 (21 d)

NC0 (7 d)138.6 ± 8.5ns (7 d)15.2 ± 3.0 (7 d)34.4 ± 5.9ns (7 d)
0 (14 d)116.2 ± 5.4 (14 d)12.2 ± 3.2 (14 d)30.6 ± 6.2ns (14 d)
1 (21 d)64.8 ± 6.5 (21 d)28.0 ± 4.8ns (21 d)31.2 ± 4.7 (21 d)

O0 (7 d)115.0 ± 10.5ns (7 d)8.6 ± 1.8ns (7 d)39.4 ± 4.8ns (7 d)
1 (14 d)100.2 ± 12.2 (14 d)7.2 ± 2.4 (14 d)44.0 ± 10.9ns (14 d)
3 (21 d)62.2 ± 6.6 (21 d)18.6 ± 5.4ns (21 d)40.8 ± 7.7ns (21 d)

P0 (7 d)113.0 ± 14.7ns (7 d)17.2 ± 2.9 (7 d)45.0 ± 7.6 (7 d)
2 (14 d)87.8 ± 8.8ns (14 d)14.0 ± 2.7 (14 d)74.0 ± 9.4 (14 d)
4 (21 d)17.8 ± 2.6 (21 d)4.6 ± 1.7ns (21 d)74.2 ± 5.4 (21 d)

aMean values within each group were compared with PC as the positive control: ns = not significant; , , and . bReported as mean ± SD.