Research Article

RAB11A Promotes Cell Malignant Progression and Tumor Formation of Prostate Cancer via Activating FAK/AKT Signaling Pathway

Figure 6

RAB11A promotes the tumor formation of prostate cancer via activating the FAK/AKT signaling pathway in vivo. (a) Tumor size (scale bar = 1 cm); (b) tumor weight and volume. (c) The mRNA expression of RAB11A in tumor tissues of mice was detected by RT-qPCR. (d) The protein levels of p-FAK/FAK and p-AKT/AKT in tumor tissues were measured by western blotting. Mice were subcutaneously injected with PC-3 cells that were transfected with si-NC or si-RAB11A. After 30 days transfection, mice were euthanized, and tumor tissues were collected. vs. si-NC.
(a)
(b)
(c)
(d)