Network Pharmacology-Based Identification of Key Targets of Ziyin Mingmu Pills Acting on Age-Related Macular Degeneration

Figure 7

Estimation of fractions of immune cells. (a) 22 immune cells were annotated by various colors. (b) The heatmap illustrating the differences in infiltrating immune cells, and the colors ranging from blue to red represent the infiltration density from low to high. (c) The Wilcoxon rank-sum test was used to accurately compare the differences, and the results showed that plasma cells ( = 0.023) in the high-risk group (blue symbol) displayed a significantly higher infiltration density. (d) The relationship between 2 hub genes and 22 infiltrating immune cells was evaluated, and there was a strong association between EGFR and immune cell content. value <0.05; value <0.01.

(a)

(b)

(c)

(d)