The Carthamus tinctorius L. and Lepidium apetalum Willd. Drug Pair Inhibits EndMT through the TGFβ1/Snail Signaling Pathway in the Treatment of Myocardial Fibrosis

Figure 9

Effect of C-L on the culture supernatant of CMECs. (a) Schematic diagram of CF culture. (b) The proliferative activity of CFs was detected by the CCK-8 method. (c, d) Effect of the culture supernatant of different CMECs on the collagen synthesis of CFs. (e, f) The contents of TGFβ1 and CTGF in the culture supernatant of CMECs were determined by ELISAs. (g) The proliferative activity of fibroblasts was detected by the CCK-8 method. (h, i) Type I and type III collagen mRNA expression in fibroblasts. C-L, drug-loaded serum containing C-L. ; ; .

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