Comparative Assessment of Three Medicinal Plants against Diabetes and Oxidative Stress Using Experimental and Computational Approaches

Table 5

Molecular docking study of EEMC, METT, and MEAC against Uricase (PDB ID: 1R4U) for antioxidant activity.

Sample	Compound	Docking score	Glide Emodel	Glide energy
EEMC	Crassifoside A	−5.35	−59.52	−47.16
	Breviscaside A	−4.16	−53.09	−43.10
	Crassifogenin C	−5.34	−53.21	−41.99
	Crassifoside D	−5.26	−55.67	−45.15
	Curcapital	−4.75	−39.26	−30.77
	Isocurculigine	−5.73	−70.01	−55.83
METT	Cyclotricuspidoside A	−6.06	−70.04	−56.64
	Cyclotricuspidoside C	−5.24	−67.78	−53.35
	Stigmast-7-en-3β-ol	−2.95	−26.46	−24.87
	α-Spinasterol	−4.26	−32.43	−25.42
	3-o-β-D-glucopyranoside	−2.74	−33.84	−30.30
	Glyceryl 1 palmitate	−3.02	−36.58	−33.96
MEAC	Stigmasterol	−3.37	−26.59	−22.17
	Beta-sitosterol	−3.44	−27.66	−23.70
	Campesterol	−4.02	−30.20	−24.95
	1,3,5-Benzenetriol	−6.22	−29.66	−21.28
	Vitamin E acetate	−3.59	−41.48	−37.40
	Squalene	−2.40	−32.13	−31.20
Standard	Ascorbic acid	−4.52	−32.91	−25.72
	Gallic acid	−5.07	−34.53	−26.13
	Quercetin	−5.15	−44.42	−34.35

EEMC: ethanol extract of M. capitulata; METT: methanol extract of T. tricuspidata; MEAC: methanol extract of A. campanulatus.