Comparative Assessment of Three Medicinal Plants against Diabetes and Oxidative Stress Using Experimental and Computational Approaches
Table 7
Toxicological property analysis of EEMC, METT, and MEAC.
Sample
Compound
Parameters
Ames toxicity
Carcinogens
Acute oral toxicity
Rate of acute toxicity (LD50, mol/kg)
EEMC
Crassifoside A
NAT
NC
III
2.5150
Breviscaside A
NAT
NC
III
2.2683
Crassifogenin C
NAT
NC
III
2.8380
Crassifoside D
NAT
NC
III
2.8786
Curcapital
NAT
NC
III
2.0528
Isocurculigine
NAT
NC
III
2.1009
METT
Cyclotricuspidoside A
NAT
NC
I
3.6250
Cyclotricuspidoside C
NAT
NC
I
3.6250
Stigmast-7-en-3β-ol
NAT
NC
III
2.4189
α-Spinasterol
NAT
NC
III
2.4107
3-o-β-D-glucopyranoside
NAT
NC
IV
1.3577
Glyceryl 1 palmitate
NAT
NC
IV
0.8172
MEAC
Stigmasterol
NAT
NC
I
2.6561
β-sitosterol
NAT
NC
I
2.6561
Campesterol
NAT
NC
I
2.8078
1,3,5-Benzenetriol
NAT
NC
III
1.7622
Vitamin E acetate
NAT
NC
IV
1.5022
Squalene
NAT
NC
III
1.5057
NAT: not Ames toxicity: NT, not carcinogen; LD: lethal dose; EEMC: ethanol extract of M. capitulata; METT: methanol extract of T. tricuspidata; MEAC: methanol extract of A. campanulatus.
