Antiproliferative, Antiangiogenic, and Antimigrastatic Effects of Oroxylum indicum (L.) Kurz Extract on Breast Cancer Cell

Figure 4

Effects of OIE on the migration of MDA-MB-231 cells. (a) Representative images of wound scratches were taken at 0, 18, and 24 hrs under the inverted microscope (40× magnification). The scale bar in the figure is 100 μm. (b) The migration rate of the cells toward the wounds was expressed as the percentage of wound closure at 18 and 24 hrs. The percentage of wound closure was normalized to the wound area at 0 hrs. The data represent the mean ± SD of three independent experiments. Bars marked with different letters are significantly different at , as determined by one-way ANOVA with the Tukey post hoc test. NA = Naïve, cells alone in media; VH = vehicle control, cells in 0.1% / of DMSO diluted in media; PAZ 4.37, BAI 3.75, and OIE 25–150 = cells were treated with pazopanib 4.37 μg/mL, baicalein 3.75 μg/mL, and O. indicum extract at ranges of 25–150 μg/mL, respectively.

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