Research Article

Cardioprotective Effects of Solidago microglossa DC. in Nicotine-Treated Hypertensive Rats

Figure 1

Representative images of the left ventricle of nicotine-treated hypertensive rats that received the EESM for 28 days. The black arrow represents an area of fibrous connective tissue deposition (scar). The black circle delimits an extensive area of fibrous tissue deposition associated with necrosis of cardiac fibers. EESM: hypertensive rats that received three different doses of the Solidago microglossa extract; HCTZ: hypertensive animals that received daily doses of hydrochlorothiazide (25 mg/kg); HE: hematoxylin and eosin stain; NC: hypertensive animals that received daily doses of the vehicle; Naïve: normotensive animals that received only the vehicle.