Research Article
Toxicity Profiling and Antihyperuricemic Activity of Goubion: A Polyherbal Formulation
Table 2
Effect of Goubion 2000 mg/kg on clinical parameters during an acute toxicity study.
| Clinical parameters | Animals | Female 1 | Female 2 | Female 3 | Male 1 | Male 2 | Male 3 |
| Tremors | − | − | − | − | − | − | Convulsions | − | − | − | − | − | − | Drowsiness | − | − | − | − | − | − | Salivation | − | − | − | − | − | − | Piloerection | + | − | − | − | + | − | Lacrimation | − | − | − | − | − | − | Consumption of food | N | N | N | N | N | N | Consumption of water | N | N | N | N | N | N | Skin changes | − | − | − | − | − | − | Mortality | − | − | − | − | − | − |
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1 “+” indicates clinical parameter observed, 2 “−” indicates clinical parameter was not observed, 3 “N” indicates normal.
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