Toxicity Profiling and Antihyperuricemic Activity of Goubion: A Polyherbal Formulation

Table 7

Effect of Goubion in hyperuricemia rat model.

Groups	Doses	Serum uric acid mg/dL	95% confidence interval for mean
			Lower bound	Upper bound
Control	—	2.96 ± 0.31	2.10	3.82
Fructose only	10% fructose water	4.84 ± 0.33	3.91	5.76
Fructose + test 1^a	10% fructose + Goubion; 15 mg/kg/day	1.52 ± 0.16^#	1.08	1.96
Fructose + test 2^b	10% fructose + Goubion; 20 mg/kg/day	1.63 ± 0.20^#	1.07	2.19
Fructose + allopurinol	10% fructose + allopurinol; 5 mg/kg/day	2.53 ± 0.25^#	1.82	3.24

¹Results are expressed as mean ± SEM (n = 5). ²One way ANOVA with posthoc Tukey was applied. ³ versus control group. ^4# versus fructose group. ^5“a”indicates Goubion 15 mg/kg, ^“b”indicates Goubion 20 mg/kg.