Research Article

Oral Application of Mother’s Own Milk for Reducing Necrotizing Enterocolitis in Preterm Infants: An Updated Meta-Analysis of RCTs

Table 1

Characteristics of the included studies.

Author, yearCountryBW, GAInterventionIntervention doseSample sizeMale (%)
InterventionControlInterventionControl

Alvarez, 2020Spain<1500 g, <32 weeksMOM0.2 ml/4 h/14 days41466056.5
Aggarwal, 2021India<32 weeksMOM and DHM0.2 ml/3 h12812853.145.4
Chen, 2021China<1000 g, <28 weeksMOM0.2 ml/4 h/5 days515352.9447.17
Ferreira, 2019Brazil<1500 g, <34 weeksMOM0.2 ml/2 h/2 days47664959
Glass, 2017USA<1500 gMOM0.2 ml/3 h/5 days17134162
Lee, 2014Korea<28 weeksMOM0.2 ml/3 h/3 days24245042
Ouyang, 2021China≤32 weeksMOM0.2 ml/3 h/10 days12712551.262.4
Rodriguez, 2011USA<1000 g, <28 weeksMOM0.2 ml/2 h/2 days9677.850
Romano-Keeler, 2016USA<32 weeksMOM and DHM0.2 ml/6 h/5 days48515041
Sharma, 2019India<1250 g, <30 weeksMOM0.2 ml/2 h/3 days595845.751.7
Sohn, 2015USA<1500 g, <30 weeksMOM0.2 ml/2 h/46 h6633.350
Sudeep, 2022India<31 weeksMOM0.2 ml/3 h666754.556.7
Zhang, 2017China<1500 gMOM0.2 ml/4 h/7 days323256.253.1