Oral Application of Mother’s Own Milk for Reducing Necrotizing Enterocolitis in Preterm Infants: An Updated Meta-Analysis of RCTs

Table 2

Cochrane risk-of-bias assessment tool 2 (ROB-2) for randomized controlled trials.

Study	1	2	3	4	5	6
Alvarez, 2020	High	Some concerns	Low	Low	Low	Some concerns
Aggarwal, 2021	Low	Some concerns	Low	Low	Low	Low
Chen, 2021	Low	Low	Low	Low	Low	Low
Ferreira, 2019	Some concerns	Low	Low	Low	Low	Low
Glass, 2017	Some concerns	High	Low	Low	Low	Some concerns
Lee, 2014	Low	Low	Low	Low	Low	Low
Ouyang, 2021	Low	Low	Low	Low	Low	Low
Rodriguez, 2011	Some concerns	Some concerns	Low	Low	Low	Low
Romano-Keeler, 2016	High	Some concerns	Low	Low	High	High
Sharma, 2019	Low	Some concerns	Low	Low	Some concerns	Some concerns
Sohn, 2015	Some concerns	Some concerns	Low	Low	Some concerns	Some concerns
Sudeep, 2022	Low	Low	Low	Low	Low	Low
Zhang, 2017	Low	Low	Low	Low	Low	Low

(1) Bias arising from the randomization process; (2) bias due to deviations from intended interventions; (3) bias due to missing outcome data; (4) bias in measurement of the outcome; (5) bias in selection of the reported result; (6) overall bias.