The Aqueous Extract of Sclerocarya birrea, Nauclea latifolia, and Piper longum Mixture Protects Striatal Neurons and Movement-Associated Functionalities in a Rat Model of Diabetes-Induced Locomotion Dysfunction

Figure 5

Effects of the aqueous extract of the SNP mixture on TNF-α (a) and INF-γ (b) levels in the striatum of T2D rats. Data are shown as mean ± SEM, n = 5;  < 0.01 and  < 0.001: significant as compared to normal control; ^# < 0.05, ^## < 0.01, and ^### < 0.001: significant as compared to diabetic control. Met 200: diabetic animals receiving metformin at 200 mg/kg b.w.; SNP 150, 300: diabetic animals receiving the aqueous extract of the mixture at 150 and 300 mg/kg b.w.

(a)

(b)