Efficiency and Mechanism Evaluation of Magnolia officinalis Water Extract in Preventing Gastric Ulcer

Table 3

Protective effects of Magnolia officinalis water extract or ranitidine in pylorus ligation ICR mice.

	Evaluation index
Groups	Ulcer index	Protection ratio (%)	Gastric juice secretion (ml)	pH value of gastric juice
Sham	0	—	0.14 ± 0.03	4.94 ± 0.52
Saline	0.75 ± 0.63^#	0	0.31 ± 0.02^#	3.12 ± 0.55^#
Magnolia officinalis water extract	0.17 ± 0.35^∗	77.7^∗	0.19 ± 0.07^∗	4.21 ± 0.47^∗
Ranitidine	0.25 ± 0.35^∗	66.6^∗	0.23 ± 0.04^∗	4.92 ± 0.74^∗

Mice were pretreated with Magnolia officinalis water extract or ranitidine (100 mg/kg). The control group received an equal volume of saline for 28 days, and then pylorus ligation was performed. After 4 h, the mice were euthanized. Values represent the mean ± S.E. (n = 10). ^# vs. sham group. ^∗ vs. saline group.