Efficiency and Mechanism Evaluation of Magnolia officinalis Water Extract in Preventing Gastric Ulcer

Table 4

Biochemical parameters of pylorus ligation in ICR mice.

	Biochemical parameters
Groups	CB2 gene expression (%)	TNF-α (pg/ml)	IL-6 (pg/ml)
Sham	100	9.1 ± 3.4	12.8 ± 4.1
Saline	113.4 ± 22.8	21.1 ± 2.6^#	245.8 ± 32.6^#
Magnolia officinalis water extract	271.3 ± 29.1^∗	17.5 ± 2.1^∗	157.2 ± 20.3^∗
Ranitidine	219.7 ± 26.3^∗	16.2 ± 2.9^∗	208.2 ± 27.5^∗

Mice were pretreated with Magnolia officinalis water extract or ranitidine (100 mg/kg). The control group received an equal volume of saline for 28 days, and then pylorus ligation was performed. After 4 h, the mice were euthanized. Values represent the mean ± S.E. (n = 10). ^# vs. sham group. ^∗ vs. saline group.