Efficiency of Biobran/MGN-3, an Arabinoxylan Rice Bran, in Attenuating Diabetes-Induced Cognitive Impairment of the Hippocampus via Oxidative Stress and IR/Akt/NF-<i>κ</i>B in Rats

<div>Photomicrographs of sections in the hippocampus of male rats. (a, b) control and Biobran-treated rats show normal polymorphic (plm), normal granular (g), and normal molecular (M) layers. (c) Section from diabetic rat showing degenerated neurons (red circle) with darkly stained pyknotic nuclei (green arrow) enveloped by large perinuclear spaces (black arrow), dilated blood vessels (black dotted arrow) in the molecular layer, and red neurons in polymorphic and granular layers (blue dotted arrow). (d) Diabetic + Biobran-treated rats show marked improvements with few cells with darkly stained nuclei and perinuclear space (red arrow) (H&amp;E, X400).</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 2: Efficiency of Biobran/MGN-3, an Arabinoxylan Rice Bran, in Attenuating Diabetes-Induced Cognitive Impairment of the Hippocampus via Oxidative Stress and IR/Akt/NF-<i>κ</i>B in Rats 

Figure 2 | Efficiency of Biobran/MGN-3, an Arabinoxylan Rice Bran, in Attenuating Diabetes-Induced Cognitive Impairment of the Hippocampus via Oxidative Stress and IR/Akt/NF-κB in Rats 