Effects of Ninjin’yoeito on Human CYP3A and Mouse CYP3A Activity

Table 1

Herb composition of Kampo formula Ninjin’yoeito (NYT).

Ingredients		Contents (g)
English name	Latin name
Poria sclerotium	Poria	4.0
Japanese angelica root	Angelicae radix	4.0
Rehmannia root	Rehmanniae radix	4.0
Atractylodes rhizome	Atractylodis rhizoma	4.0
Ginseng	Ginseng radix	4.0
Cinnamon bark	Cinnamomi cortex	3.0
Citrus unshiu peel	Aurantii nobilis pericarpium	2.5
Polygala root	Polygalae radix	2.0
Peony root	Paeoniae radix	2.0
Astragalus root	Astragali radix	1.5
Schisandra fruit	Schisandrae fructus	1.0
Glycyrrhiza	Glycyrrhizae radix	1.0

Approximate 6700 mg of dried water extract of NYT is prepared in a GMP-standardized factory of Kracie Pharma, Ltd. (Japan) based on the above-described composition.