Effects of Ninjin’yoeito on Human <i>CYP3A</i> and Mouse <i>CYP3A</i> Activity

<table class="table-group" id="tab4"><tr><td><table class="table"><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr class="thead"><td class="align_left" rowspan="2">Samples</td><td class="align_center" colspan="2">IC<sub>50</sub> (mg/mL)</td></tr><tr class="thead"><td class="align_center">Reversible inhibition</td><td class="align_center">TDI</td></tr><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr><td class="align_left">GFJ</td><td class="align_center">0.693</td><td class="align_center">0.329</td></tr><tr><td class="align_left">NYT</td><td class="align_center">0.805</td><td class="align_center">0.252</td></tr><tr class="table-tr"><td colspan="3"><hr class="tbody-hr"/></td></tr></table></td></tr><tr class="table-fn"><td><div>GFJ, grapefruit juice; NYT, Ninjin’yoeito; TDI, time-dependent inhibition.<br/></div></td></tr></table>

<div>The half-maximum inhibitory concentration (IC<sub>50</sub>) of GFJ and NYT on CYP3A.</div>

Evidence-Based Complementary and Alternative Medicine

tab4

Table 4

Table 4: Effects of Ninjin’yoeito on Human <i>CYP3A</i> and Mouse <i>CYP3A</i> Activity 

Evidence-Based Complementary and Alternative Medicine

Effects of Ninjin’yoeito on Human CYP3A and Mouse CYP3A Activity

Table 4