Effects of Ninjin’yoeito on Human CYP3A and Mouse CYP3A Activity

Table 5

Effect of NYT on CYP3A4 mRNA expression.

Samples	mRNA relative expression (CYP3A4/GAPDH)	% (vs. rifampicin)
0.1% DMSO	1.00 ± 0.10	—
20 μmol/L (16.5 mg/L) rifampicin	135 ± 11	—
0.01 mg/L NYT	2.54 ± 0.11	1.75
0.1 mg/L NYT	11.2 ± 0.2	7.72
1 mg/L NYT	1.06 ± 0.05	127.4

NYT, Ninjin’yoeito.