Association of Kinase-Insert-Domain-Containing Receptor Polymorphisms with Glioma Susceptibility in a Chinese Population: A Hospital-Based Case-Control Study

Table 4

The univariate analysis: results of gene frequency comparison between two groups.

	Frequency			Unadjusted
	Case	Control		OR (95% CI)
1559
Genotype, n (%)			0.001
TT	180 (38.7)	261 (49.5)		1.00
CT	211 (45.4)	214 (40.6)		1.43 (1.09, 1.87)	0.009
CC	74 (15.9)	52 (9.9)		2.06 (1.38, 3.09)	<0.001
Allele, n (%)			<0.001
T	571 (61.4)	736 (69.8)		1.00
C	359 (38.6)	318 (32.2)		1.46 (1.21, 1.75)	<0.001
Dominant, n (%)			0.001
CC + CT	285 (61.3)	266 (50.5)		1.00
TT	180 (38.7)	261 (49.5)		1.55 (1.21, 2.00)	0.001
Recessive, n (%)			0.005
CT + TT	391 (84.1)	475 (90.1)		1.00
CC	74 (15.9)	52 (9.9)		1.73 (1.18, 2.53)	0.004
9702
Genotype, n (%)			0.024
GG	315 (67.7)	384 (72.9)		1.00
GA	124 (26.7)	130 (24.7)		1.16 (0.87, 1.55)	0.304
AA	26 (5.6)	13 (2.5)		2.44 (1.23, 4.82)	0.008
Allele, n (%)			0.014
G	754 (81.1)	898 (85.2)		1.00
A	176 (18.9)	156 (14.8)		1.34 (1.06, 1.70)	0.014
Dominant, n (%)			0.075
GG	315 (67.7)	384 (72.9)		1.00
GA + AA	150 (32.3)	143 (27.1)		1.28 (0.97, 1.68)	0.078
Recessive, n (%)			0.014
GG + GA	439 (94.4)	514 (97.5)		1.00
AA	26 (5.6)	13 (2.5)		2.34 (1.19, 4.61)	0.012