Research Article
Electroacupuncture Alleviates Pain Responses and Inflammation in Collagen-Induced Arthritis Rats via Suppressing the TLR2/4-MyD88-NF-κB Signaling Pathway
Figure 1
Experimental design for the effect of EA on CIA rats (experiment 1 and experiment 2). Male SD rats were initially immunized at the base of the tail on day 0 and boosted on day 7. From day 14 to day 42, rats in the CIA + EA group and the CIA + OxPAPC group received EA intervention or inhibitor injection every day, respectively. From day 0 to day 42, paw edema and pain responses were tested weekly in each group of rats.